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Parkinson's disease affects 10 million people worldwide and has no cure. The underlying mechanism — alpha-synuclein protein misfolding into toxic Lewy bodies — is being mapped at scale using distributed molecular dynamics simulation. Every chunk your computer solves contributes to understanding how this protein aggregates and how it can be stopped, providing data to researchers developing treatments that could halt neurodegeneration before symptoms become severe.
This research is supported by and contributes data to The Michael J. Fox Foundation for Parkinson's Research and Columbia University Neuroscience, which have invested over $1 billion in Parkinson's research and are leading the push for computational approaches to the disease.