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Lung cancer is the leading cause of cancer death worldwide — 1.8 million deaths per year. When caught at Stage I, 5-year survival is 61%. When caught at Stage IV (as most cases are), survival falls to 6%. The solution is early detection via blood-based biomarkers. Your compute runs genomic alignment and machine learning tasks that build the biomarker atlas researchers need to design a blood test that detects lung cancer before symptoms appear. Supported by the National Cancer Institute and MD Anderson Cancer Center.